5 Things to Know About CBDV | BayMedica

5 Essential Things to Know About Cannabidivarin (CBDV)

Dec 5, 2024

The Rare Cannabinoid for Health and Wellness

Cannabidivarin (CBDV) is quickly gaining attention in the cannabinoid industry for its unique properties and potential applications in health and wellness. This rare, non-intoxicating compound from the Cannabis sativa plant is increasingly the focus of scientific research and product development.

Here are five essential things to know about CBDV:

1. CBDV is a Rare Cannabinoid

Unlike well-known cannabinoids such as tetrahydrocannabinol (THC) and cannabidiol (CBD), which are found in high concentrations in most cannabis plants, CBDV is considered a rare or minor cannabinoid. It typically occurs in very small amounts in traditional, non-modified cannabis strains, making it difficult and expensive to extract directly from the plant. Thanks to biosynthesis and chemical synthesis advancements, CBDV can now be produced at scale, opening the door for its use in a wide range of consumer health and wellness products.

2. CBDV is Non-Intoxicating

One of the key advantages of CBDV is that, like CBD, it is non-intoxicating. This means it does not cause the psychoactive effects typically associated with THC, making it a safer option for users seeking therapeutic benefits without the “high.” Human clinical trials have shown that CBDV has an excellent safety profile, even at high doses, with no serious side effects reported1. This makes it an attractive ingredient for many therapeutic applications.

3. CBDV Interacts with Many Cannabinoid Receptors

CBDV interacts with several receptors in the body’s endocannabinoid system (ECS), which regulates pain, inflammation, and mood. Research shows that CBDV acts as an agonist for TRPA1, TRPV1, and TRPV2 receptors—these receptors are involved in pain perception, inflammation, and neurological processes. CBDV also functions as an antagonist of GPR55 and an inverse agonist of GPR6, which has been linked to neurological signaling.

4. CBDV is One of the Most Researched Rare Cannabinoids

Despite being a minor cannabinoid, CBDV is one of the most extensively researched. Its potential anti-inflammatory and neuroprotective effects are being explored in various studies. Conditions such as autism spectrum disorder (ASD), epilepsy, inflammatory bowel disease (IBD), acne, alopecia, nausea, and pain have all been researched in connection with CBDV. This broad range of research highlights the therapeutic versatility of CBDV, making it an exciting prospect for future wellness products.

5. CBDV is Being Studied in Clinical Trials

While CBDV is not approved for therapeutic use, it is undergoing several human clinical trials to evaluate its potential benefits. Trials are examining CBDV’s use in managing conditions like autism, Prader-Willi Syndrome, alopecia, and attention deficit hyperactivity disorder (ADHD), thus CBDV may have implications in providing a calming and stabilizing activity from a neurological perspective. As research continues, CBDV could become a key ingredient in the development of new cannabinoid-based treatments across various health conditions.


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Interested in learning more about the potential health benefits of CBDV?

If you’re interested in learning more about the scientific research surrounding CBDV and its potential applications, you can download BayMedica’s comprehensive CBDV whitepaper.

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References:

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544893/
  2. https://pubmed.ncbi.nlm.nih.gov/21726418/
  3. https://pubmed.ncbi.nlm.nih.gov/22970845/
  4. https://pubmed.ncbi.nlm.nih.gov/24282673/
  5. https://pubmed.ncbi.nlm.nih.gov/23902479/