5 Things to Know About CBDV | BayMedica

5 Things to Know About CBDV

Apr 23, 2022

5 Things to Know About Cannabidivarin (CBDV)

1. CBDV is a rare cannabinoid

Unlike well-known cannabinoids tetrahydrocannabinol (THC) and cannabidiol (CBD) which are abundant in the Cannabis plant, CBDV is known as a rare, or minor, cannabinoid and is typically found in minuscule quantities in non-modified strains of the plant.

2. CBDV is non-intoxicating

CBDV is a non-intoxicating rare cannabinoid. In addition, CBDV demonstrated a good safety profile in human clinical trials, with no adverse side effects reported¹ even at the highest doses tested.

3. CBDV interacts with many cannabinoid receptors

Scientific literature suggests that CBDV acts as an agonist of TRPA1, TRPV1 and TRPV2 receptors, an inverse agonist of GPR6, an antagonist of GPR55 and may be an inhibitor of endocannabinoid 2-AG production.

4. CBDV is one of the most researched rare cannabinoids

CBDV has been researched for its potential anti-inflammatory, anti-convulsant and neurological effects and has been the subject of studies in autism, epilepsy, acne, alopecia, inflammatory bowel disease, nausea, and pain.

5. CBDV is being studied in clinical trials

Currently, there is no regulatory approval of CBDV for the therapeutic use for any condition, but it’s being studied in human clinical trials for a number of potential therapeutic uses such as autism, alopecia, Prader-Willi Syndrome and attention deficit hyperactive disorder (ADHD).

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Sources:

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544893/
  2. https://pubmed.ncbi.nlm.nih.gov/21726418/
  3. https://pubmed.ncbi.nlm.nih.gov/22970845/
  4. https://pubmed.ncbi.nlm.nih.gov/24282673/
  5. https://pubmed.ncbi.nlm.nih.gov/23902479/